Arabidopsis Interactome Mapping Consortium. (Dreze M, Carvunis AR, Charloteaux B, Galli M, Pevzner SJ, Tasan M co-first authors; Braun P, Vidal M, Ecker JR, Hill DE co-corresponding authors) Evidence for network evolution in an Arabidopsis interactome map. Science 2011; 333:601-7. Commentary, Science. Research Highlight, Nat Rev Genet.Our laboratory studies cell division, cell division and chromosome segregation errors in cancer, and the impact of these errors on cancer genome structure. We use genetics, biochemistry and live-cell imaging. We developed a method to combine long-term live-cell imaging with single cell isolation and single cell genomics (Look-Seq). Accounts of the complex cellular networks that underlie plant-specific functions are missing. We describe a proteome-wide binary protein-protein interaction map for the interactome network of the plant Arabidopsis thaliana containing ~6,200 highly reliable interactions between ~2,700 proteins. Community analyses of the resulting network shows ... dfcionline.org Arabidopsis Interactome Mapping Consortium. (Dreze M, Carvunis AR, Charloteaux B, Galli M, Pevzner SJ, Tasan M co-first authors; Braun P, Vidal M, Ecker JR, Hill DE co-corresponding authors) Evidence for network evolution in an Arabidopsis interactome map. Science 2011; 333:601-7. Commentary, Science. Research Highlight, Nat Rev Genet.Electronic data capture and tracking: Manage, clean, store, and retrieve clinical trials data; create electronic case report forms. Users: Clinical researchers, Research staff. Institutions: DF/HCC, Outside participating sites. Access and support: IS Service Hub instructions.Figure 3 Screenshot Command: cctk.exe -h --InternalSpeaker. We have now made the comparison with DFCI. Except for the partial ability to change the UEFI, CCTK is more fine-tunable than DFCI. A ...1984 - Dana-Farber Cancer Institute establishes the Molecular Biology Core Facilities (MBCF) to supply state of the art molecular biology tools to Institute researchers. 1991 - Dana-Farber investigators help introduce the use of naturally occurring growth hormones following high-dose chemotherapy, making bone marrow transplantation safer and ...Afterwards, she was awarded a fellowship from the Harvard Society of Fellows. From 2007 until 2010, she was an Assistant Professor in the Computational Biology Program at Memorial Sloan-Kettering Cancer Center. Dr. Michor is the director of the Dana-Farber Cancer Institute Center for Cancer Evolution.Bradley E. Bernstein, MD, PhD. Professor of Pathology and Cell Biology, Harvard Medical School. Chair, Department of Cancer Biology, Dana-Farber Cancer Institute Director, Broad Epigenomics Program and Broad Gene Regulation Observatory. [email protected]. Principal investigator Baochun Zhang, MB, PhD Assistant Professor of Medicine, Harvard Medical School Division of Hematologic Neoplasia Department of Medical Oncology Department of Cancer Immunology and Virology Dana-Farber Cancer Institute Office location: Mayer 521A Mail address: 450 Brookline Avenue, Mayer 521A, Boston, MA 02215 [email protected] Office phone: William C. Hahn, MD, PhD, has been engaged in clinical care and research at Dana-Farber since 1996. He is the William Rosenberg Professor of Medicine and an Institute Member of the Broad Institute of MIT and Harvard. He received his AB in Biochemical Sciences, PhD in Immunology, and MD all from Harvard University and completed his clinical ...Dec 1, 2000 · This approach correctly predicts a functional category for 72% of the 1,393 characterized proteins with at least one partner of known function, and has been applied to predict functions for 364 previously uncharacterized proteins. A global analysis of 2,709 published interactions between proteins of the yeast Saccharomyces cerevisiae has been performed, enabling the establishment of a single ... Dec 1, 2000 · This approach correctly predicts a functional category for 72% of the 1,393 characterized proteins with at least one partner of known function, and has been applied to predict functions for 364 previously uncharacterized proteins. A global analysis of 2,709 published interactions between proteins of the yeast Saccharomyces cerevisiae has been performed, enabling the establishment of a single ... Apr 26, 2018 · Dana-Farber's Ann Gross, PhD, RN, Senior Vice President and Chief Nursing Officer, discusses the evolving role of nursing within oncology and keeping up with cancer advances and technology. Read more in the Boston Globe ( The human ORFeome collection is made possible through support from the High-Tech Fund of the Dana-Farber Cancer Institute, The Ellison Foundation (Boston, MA), and by grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medical Sciences. Interactome Projects at CCSB. H uman interactome mapping is the flagship project of CCSB. A first map of the human binary interactome ( Rual et al Nature 2005) was obtained by yeast two-hybrid (Y2H) screening for direct, binary interactions within a "Space I" matrix of ~8,000 x 8,000 ORFs contained in Human ORFeome v1.1 ( Rual et al Genome Res ... Acknowledgments. CCSB interactome mapping and ORFeome cloning efforts are supported by federal grants from the National Human Genome Research Institute, the National Cancer Institute and the National Science Foundation, and by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation. Myles Brown, MD, is a Professor of Medicine at DFCI and HMS as well as a practicing physician in oncology at the Brigham And Women's Hospital.Dr. Brown's research laboratory focuses on elucidating the epigenetic factors underlying the action of steroid hormones. Robert and Renée Belfer’s transformative cumulative Dana-Farber investment of more than $25 million launched the Robert A. and Renée E. Belfer Center for Applied Cancer Science. Their generosity enabled the Belfer Center to integrate its scientific teams, produce innovative cancer models, partner with industry leaders, and accelerate the ...Defy Cancer. The Dana-Farber Campaign will advance our mission by raising funds to defy cancer with revolutionary science, extraordinary care, and exceptional expertise. Dana-Farber Brigham Campaign: We specialize in cancer. And you. Dana-Farber Brigham Cancer Center has been New England's top-ranked cancer center for over 20 years.Microsoft DFCI Scenarios¶ Overview¶ Microsoft leverages DFCI to provide automated UEFI settings management via Microsoft Intune. Intune provides the IT manager with abstracted, easy button settings that are generally applicable to all platforms, for example, disable booting USB devices or disable all cameras. CCSB interactome mapping and ORFeome cloning efforts are supported by federal grants from the National Human Genome Research Institute, the National Cancer Institute and the National Science Foundation, and by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation. Natasha M. Archer, MD. Pediatric Hematology/Oncology. No Ratings Available - Why Not? The human ORFeome collection is made possible through support from the High-Tech Fund of the Dana-Farber Cancer Institute, The Ellison Foundation (Boston, MA), and by grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medical Sciences. We are building out our Intune AutoPilot builds and wondering if HP is implementing or planning to enable/allow MS's DCFI model for direct config of Bios? I believe the plan is to support modern management natively. However whether that will be DFCI or something else is behind the scenes, and currently undefined.Michor is the director of the Dana-Farber Cancer Institute Center for Cancer Evolution. She has been the recipient of the Theodosius Dobzhansky Prize of the Society for the Study of Evolution, the Alice Hamilton Award, the Vilcek Prize for Creative Promise in Biomedical Science, the 36th Annual AACR Award for Outstanding Achievement in Cancer ... Defy Cancer. The Dana-Farber Campaign will advance our mission by raising funds to defy cancer with revolutionary science, extraordinary care, and exceptional expertise. Dana-Farber Brigham Campaign: We specialize in cancer. And you. Dana-Farber Brigham Cancer Center has been New England's top-ranked cancer center for over 20 years. Welcome to the C. elegans Fragment database. This website is an interface to our interaction data focused on showing not just which proteins interact, but which regions of the proteins mediate the interactions. It allows you to display a list of interactions using one or more of your favorite proteins as search terms. From this list, you can ... DFCI enables Windows to pass management commands from Intune to UEFI (Unified Extensible Firmware Interface). In Intune, use this feature to control BIOS settings. Typically, firmware is more resilient to malicious attacks. It limits end users control over the BIOS, which is good in a compromised situation.On December 3, 1994, 39-year-old Boston Globe health reporter Betsy Lehman died of complications of an overdose of cyclophosphamide, a chemotherapeutic agent she received at the Dana-Farber Cancer Institute for treatment of breast cancer. The media reported the event intensively, with 28 front-page headlines over the next 3 years.Onsite: Full time on Campus. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where ...CCSB interactome mapping and ORFeome cloning efforts are supported by federal grants from the National Human Genome Research Institute, the National Cancer Institute and the National Science Foundation, and by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation.Under Platform, select Windows 10 and later. Under Profile type, select Templates > Device Firmware Configuration Interface and then select Create. See Use DFCI profiles on Windows devices in Microsoft Intune for complete instructions, including: Create your Azure AD security groups. Create the profiles.Frontiers in Biostatistics Seminar Tuesday October 17, 2023 @ 1pm ET Center for Life Sciences Building, Room 11081 Title TBA William Lotter, PhD Assistant Professor, Dana-Farber Cancer Institute and Harvard […]Our mission is to serve patients, present and future, by enabling, improving, and transforming DFCI research, patient care, and operations through excellence in informatics and analytics. We are working toward a future in which DFCI is a rapid-learning health system, enabled by an efficient, sustainable informatics and analytics ecosystem that ... Acknowledgments. CCSB interactome mapping and ORFeome cloning efforts are supported by federal grants from the National Human Genome Research Institute, the National Cancer Institute and the National Science Foundation, and by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation.Bradley E. Bernstein, MD, PhD. Professor of Pathology and Cell Biology, Harvard Medical School. Chair, Department of Cancer Biology, Dana-Farber Cancer Institute Director, Broad Epigenomics Program and Broad Gene Regulation Observatory. [email protected]. WTRL s home to the world famous weekly WTRL Team Time Trial that takes every Thursday. In partnersip with Zwift (www.zwift.com), we also host ZWIFT RACING LEAGUE, ZWIFT DUATHLON LEAGUE and ZWIFT RUNNING LEAGUE Dana-Farber Cancer Institute, Boston, Massachusetts. 431,113 likes · 3,555 talking about this. Dana-Farber Cancer Institute is committed to providing expert, compassionate care. May 1, 2005 · In a November 2004 Boston Globe retrospective on the Lehman and Bateman overdoses, reporter Scott Allen described the Dana-Farber as "one of the most safety-conscious hospitals in America." In fact, we reported to the Globe 8 years of data from our confidential incident reporting system. Although it showed rare errors, there were no deaths or serious injuries from chemotherapy-related errors ... Robert and Renée Belfer’s transformative cumulative Dana-Farber investment of more than $25 million launched the Robert A. and Renée E. Belfer Center for Applied Cancer Science. Their generosity enabled the Belfer Center to integrate its scientific teams, produce innovative cancer models, partner with industry leaders, and accelerate the ...Variable / Field Name,Form Name,Section Header,Field Type,Field Label,"Choices, Calculations, OR Slider Labels",Field Note,Text Validation Type OR Show Slider Number,Text ValidatiExperimental Therapeutics Core. The Experimental Therapeutics (ETx) Core is a preclinical resource to Dana-Farber Cancer Institute (DFCI) researchers and collaborators for conducting in vivo pharmacological studies. Studies will be run at a 14,000-square-foot preclinical facility shared with the Lurie Family Imaging Center (LFIC) that features ...The human ORFeome collection is made possible through support from the High-Tech Fund of the Dana-Farber Cancer Institute, The Ellison Foundation (Boston, MA), and by grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medical Sciences. William C. Hahn, MD, PhD, has been engaged in clinical care and research at Dana-Farber since 1996. He is the William Rosenberg Professor of Medicine and an Institute Member of the Broad Institute of MIT and Harvard. He received his AB in Biochemical Sciences, PhD in Immunology, and MD all from Harvard University and completed his clinical ... Overview. The Device Firmware Configuration Interface (DFCI) brings new levels of security and usability to PC configuration management. It is a new feature of UEFI that enables secure programmatic configuration of hardware settings that are typically configured within a BIOS menu by a human. Through our 12 specialized disease treatment centers, experts from our two organizations, Dana-Farber Cancer Institute and Brigham and Women’s Hospital, work together as one team to offer the most advanced treatments with compassion and care that makes all the difference. For over 20 years, US News & World Report has named Dana-Farber Brigham ... WTRL s home to the world famous weekly WTRL Team Time Trial that takes every Thursday. In partnersip with Zwift (www.zwift.com), we also host ZWIFT RACING LEAGUE, ZWIFT DUATHLON LEAGUE and ZWIFT RUNNING LEAGUE Franziska Michor, PhD, serves as the Director of the Center for Cancer Evolution. She is a Professor of Computational Biology in the Department of Data Sciences at the Dana-Farber Cancer Institute, in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health, and in the Department of Stem Cell and Regenerative Biology at Harvard University. The Breast Cancer Advocacy Group (BCAG) contributes an informed patient voice to breast cancer research. The advocates collaborate with breast cancer investigators within and beyond DF/HCC in planning and reviewing translational and clinical research in all its stages, with the goal of finding better treatments, improving patient outcomes, and ...Variable / Field Name,Form Name,Section Header,Field Type,Field Label,"Choices, Calculations, OR Slider Labels",Field Note,Text Validation Type OR Show Slider Number,Text ValidatiPeople & Contacts. Adam Bass. [email protected]. Adam Bass is an Associate Professor of medicine at Harvard Medical School, a physician/scientist at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital and also is an associate member of the Broad Institute. Dr.Principal investigator Baochun Zhang, MB, PhD Assistant Professor of Medicine, Harvard Medical School Division of Hematologic Neoplasia Department of Medical Oncology Department of Cancer Immunology and Virology Dana-Farber Cancer Institute Office location: Mayer 521A Mail address: 450 Brookline Avenue, Mayer 521A, Boston, MA 02215 [email protected] Office phone: CCSB interactome mapping and ORFeome cloning efforts are supported by federal grants from the National Human Genome Research Institute, the National Cancer Institute and the National Science Foundation, and by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation.Microsoft DFCI Scenarios¶ Overview¶ Microsoft leverages DFCI to provide automated UEFI settings management via Microsoft Intune. Intune provides the IT manager with abstracted, easy button settings that are generally applicable to all platforms, for example, disable booting USB devices or disable all cameras. Move the mouse over the map and this page will show you the Maidenhead locator, latitude/longitude coordinates in WGS84 (both decimal and DMS), UTM as well as french Lambert II and DFCI. You can zoom the map with the help of the mouse wheel or the control on the upper left part of the map. Interactome Projects at CCSB. H uman interactome mapping is the flagship project of CCSB. A first map of the human binary interactome ( Rual et al Nature 2005) was obtained by yeast two-hybrid (Y2H) screening for direct, binary interactions within a "Space I" matrix of ~8,000 x 8,000 ORFs contained in Human ORFeome v1.1 ( Rual et al Genome Res ...Here we present a fourth version of the human ORFeome, human ORFeome 7.1. W ith the Mammalian Gene Collection (MGC) resource as a starting point, we successfully cloned 18,414 human ORFs, representing at least 15,415 human genes, as mini-pools of PCR-amplified products. The human ORFeome version 7.1 (hORFeome v7.1) collection, includes the ... Bradley E. Bernstein, MD, PhD. Professor of Pathology and Cell Biology, Harvard Medical School. Chair, Department of Cancer Biology, Dana-Farber Cancer Institute Director, Broad Epigenomics Program and Broad Gene Regulation Observatory. [email protected] of result from your search terms Click ORF ID for additional information. The isoform project is made possible through support from the High-Tech Fund of the Dana-Farber Cancer Institute, The Ellison Foundation (Boston, MA), and by grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medical Sciences. Franziska Michor, PhD, serves as the Director of the Center for Cancer Evolution. She is a Professor of Computational Biology in the Department of Data Sciences at the Dana-Farber Cancer Institute, in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health, and in the Department of Stem Cell and Regenerative Biology at Harvard University. The human ORFeome collection is made possible through support from the High-Tech Fund of the Dana-Farber Cancer Institute, The Ellison Foundation (Boston, MA), and by grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medical Sciences.Dana-Farber Cancer Institute, Boston, Massachusetts. 431,113 likes · 3,555 talking about this. Dana-Farber Cancer Institute is committed to providing expert, compassionate care. Submitting new studies and managing ongoing studies in treatment-based (clinical) research.network name description non-loop nodes count non-loop edges count loop-only nodes count loop edges count; WI-2007: interactions from 2007 Y2H screen: 1465About Human Isoform Project. C omplete understanding of the biology of the human genome will not be possible without understanding the full complement of functional proteins, or proteome, that the genome encodes. The latest GENCODE effort reaffirms the ~20,000 protein-coding genes in the human genome, but also emphasizes that full protein ...The human ORFeome version 5.1 (hORFeome v5.1) collection, includes the previous human ORFeome releases (v1.1 and 3.1), with the addition of 3,272 newly transferred ORFs from MGC templates. h ORFeome v5.1 represents a central resource of cloned human ORFs which can be transferred easily to Gateway compatible destination vectors for various ...List of result from your search terms Click ORF ID for additional information. Dana-Farber Cancer Institute. Mass General Brigham. English Eng English Eng; Ver en Español Посмотреть ... CCSB Interactome Mapping and ORFeome cloning efforts are supported by funding from the Dana-Farber Cancer Institute Strategic Initiative, The Ellison Foundation and the W. M. Keck Foundation and by federal grants from the National Human Genome Research Institute and the National Cancer Institute of the National Institutes of Health, the National Science Foundation, and the US Department of Energy.William C. Hahn, MD, PhD, has been engaged in clinical care and research at Dana-Farber since 1996. He is the William Rosenberg Professor of Medicine and an Institute Member of the Broad Institute of MIT and Harvard. He received his AB in Biochemical Sciences, PhD in Immunology, and MD all from Harvard University and completed his clinical ... The Dana–Farber/Harvard Cancer Center is the largest National Cancer Institute (NCI) designated Comprehensive Cancer Center in the nation. Founded in 1997, DF/HCC is an inter-institutional research enterprise that unites all of the cancer research efforts of the Harvard affiliated community. The primary goal of the Cancer Center is to ...The Gateway-based full-length ORFeome cloning strategy has had tremendous success in numerous projects in the Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute Our ORF-cloning pipeline has the following steps: i) Predicted ORFs are precisely PCR-amplified between annotated initiation and termination codons (ATG to STOP), using either a cDNA library or RT-PCR as ... Internal ID: 903 Entrez Gene ID: 8405 BC number: BC001269 UCSC; BC003385 UCSC; Clone Result: PCR Attempted: YES Clone Succeeded: YES Consolid Plate: 11009 Consolid Position: A01 The DFCI enrollment process is kicked off when a PC is enrolled into Intune and has a matching DFCI Profile. Enrollment includes Intune requesting enrollment packets from APS, sending the packets to the Windows UEFI configuration service provider (CSP) endpoints , the CSP writes the packets to UEFI variables, and triggers an OS reboot to allow UEFI firmware to process the DFCI packets. Robert and Renée Belfer’s transformative cumulative Dana-Farber investment of more than $25 million launched the Robert A. and Renée E. Belfer Center for Applied Cancer Science. Their generosity enabled the Belfer Center to integrate its scientific teams, produce innovative cancer models, partner with industry leaders, and accelerate the ...The Refresh From Network server may run on the HOST system. A Device Under Test (DUT) to be tested, with the new DFCI supported firmware, running the current version of Windows. To validate your DFCI test framework, you can use the Project Mu Tiano Platforms QemuQ35Pkg virtual system as the DUT. String processing. One of the most common data wrangling challenges involves extracting numeric data contained in character strings and converting them into the numeric representations required to make plots, compute summaries, or fit models in R. Also common is processing unorganized text into meaningful variable names or categorical variables. Move the mouse over the map and this page will show you the Maidenhead locator, latitude/longitude coordinates in WGS84 (both decimal and DMS), UTM as well as french Lambert II and DFCI. You can zoom the map with the help of the mouse wheel or the control on the upper left part of the map. Patients at Mass. General and Brigham and Women's and their community hospitals and physician groups as well as patients at Mass. Eye and Ear and Dana-Farber are eligible to share in an $18.4-million class-action settlement of a claim involving information the health-care providers' Web site may have shared with Facebook and Google - but they have to sign up by Dec. 15. Read more.Windows 10 With Windows Autopilot Deployment and Intune, you can manage Unified Extensible Firmware Interface (UEFI) settings after they're enrolled by using the Device Firmware Configuration Interface (DFCI). DFCI enables Windows to pass management commands from Intune to UEFI for Autopilot deployed devices.
Harvard University. Sandp oscillator
William C. Hahn, MD, PhD, has been engaged in clinical care and research at Dana-Farber since 1996. He is the William Rosenberg Professor of Medicine and an Institute Member of the Broad Institute of MIT and Harvard. He received his AB in Biochemical Sciences, PhD in Immunology, and MD all from Harvard University and completed his clinical ... Patients at Mass. General and Brigham and Women's and their community hospitals and physician groups as well as patients at Mass. Eye and Ear and Dana-Farber are eligible to share in an $18.4-million class-action settlement of a claim involving information the health-care providers' Web site may have shared with Facebook and Google - but they have to sign up by Dec. 15. Read more.Guilty Gear Xrd REV 2. Dead or Alive 6. Power Rangers: Battle for the Grid. Marvel vs. Capcom: Infinite. Ultra Street Fighter IV. BlazBlue: Cross Tag Battle. Chaos Code: NSoC. Guilty Gear XX AC+R. Dengeki Bunko Fighting Climax Ignition.See a list of all the DFCI profile settings and their descriptions on Windows 10/11 client devices. Use these settings in a configuration profile to control UEFI firmware layer features using Microsoft Intune policy. You can manage the CPU, built-in hardware, and boot options on Windows 10/11 client devices using Microsoft Intune.Afterwards, she was awarded a fellowship from the Harvard Society of Fellows. From 2007 until 2010, she was an Assistant Professor in the Computational Biology Program at Memorial Sloan-Kettering Cancer Center. Dr. Michor is the director of the Dana-Farber Cancer Institute Center for Cancer Evolution.Self Ejecting. Self Ejecting is the term used to describe a stud that is, when unlocked, raised above the panel by a spring located under it. The ejection will provide a visual indication that the stud is unlocked. It also holds the stud against the panel to ease the removal from and/or alignment with the support and its receptacle.DFCI's Communications Department offers a Lab Website Program (LWP) at no cost, utilizing DFCI branded templates designed for non-technical professionals to learn and use. Contact to get started: Luise Dittrich - Project Manager, LWP.Multi-disciplinary, integrated expertise | problem solving and support For clinical, research, and operational missionsWe would like to show you a description here but the site won’t allow us.Arabidopsis Interactome Mapping Consortium. (Dreze M, Carvunis AR, Charloteaux B, Galli M, Pevzner SJ, Tasan M co-first authors; Braun P, Vidal M, Ecker JR, Hill DE co-corresponding authors) Evidence for network evolution in an Arabidopsis interactome map. Science 2011; 333:601-7. Commentary, Science. Research Highlight, Nat Rev Genet.Access requires you be on the DFCI network, or if remote, use Cisco AnyConnect VPN. Dana-Farber owns a limited site license, so the software is free to all DFCI users. There is a limit of one license per user on one computer. You can find training and tutorial materials from the GraphPad web site: Learn Prism.We present a new version of the human ORFeome, human ORFeome 8.1 containing clonally-derived and sequence-confirmed ORFs as a set of Gateway Entry clones ready for transfer to Gateway-compatible expression vectors. W ith the Mammalian Gene Collection (MGC) resource as our original starting point, we obtained 12,230 clonal isolates, representing ....
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